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butabarbital will lower the level or impact of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.cannabidiol will raise the level or result of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Watch Closely. Look at reducing the dose of delicate CYP2C19 substrates, as clinically correct, wh